They are derived from prokaryotic bacteria, eukaryotic microorganisms, plants and various animal organisms. Natural products are still one of the major sources of new drug molecules today. įor this reason, discovery of new antibiotics is an exclusively important objective. Currently, its impact is considerable with treatment failures associated with multidrug-resistant bacteria and it has become a global concern to public health. In this review, we focused on the use of antimicrobial testing methods for the in vitro investigation of extracts and pure drugs as potential antimicrobial agents.Īfter the revolution in the “golden era”, when almost all groups of important antibiotics (tetracyclines, cephalosporins, aminoglycosides and macrolides) were discovered and the main problems of chemotherapy were solved in the 1960s, the history repeats itself nowadays and these exciting compounds are in danger of losing their efficacy because of the increase in microbial resistance. Antimicrobial susceptibility testing can be used for drug discovery, epidemiology and prediction of therapeutic outcome.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |